Top 5 Glucosamine Supplements For Dogs in 2025
Don't buy glucosamine supplements for your dog until you read this!
Choosing the right glucosamine for your dog relies on three key points: Safe Ingredients, Effectiveness, and Value for money.
Most people are likely giving their dogs the cheapest supplements or the most expensive, which are equally popular choices because of the price or lack of knowledge. That is if they’re using a supplement at all, as many choose to skip this key step if their dog isn’t suffering.
However, if your dog is suffering from joint pain and discomfort, a quality glucosamine supplement may help. It is one of the most popular supplements for canines, and for good reason. Glucosamine is a safe and natural way to help improve your dog’s joint function and quality of life. Glucosamine can restore joint health and increase mobility, has anti-inflammatory effects, and improves lubrication in your dog’s joints.[1] It is naturally produced in the body, but over time, a dog’s natural production can become inadequate at preventing joint damage.[2]
One of the most important things to look for in terms of glucosamine supplements is what other ingredients are present. A few other complementary ingredients that work together with glucosamine are chondroitin, MSM, and ascorbic acid (Vitamin C).[3,4]
Finally – you’ll want a Glucosamine supplement that contains safe ingredients and is transparent about dosages. We’ve found that some companies throw in filler ingredients that either do absolutely nothing for your pet or cause more harm than good. It’s important to know how to spot the bad ingredients and ensure they contain the proper dosage of Glucosamine.
It can be difficult to know which are the best glucosamine supplements for dogs. That’s why PupGrade has compiled months of research about this emerging category. We’ll show you what to look for and what to avoid when picking the perfect dog joint support, and how they can help transform your pup.
How to Tell if Your Dog Needs Glucosamine
The goal of glucosamine is to ease joint pain and discomfort in your dog, especially symptoms associated with canine arthritis. Arthritis can be triggered by a few things, such as injury, infections, or underlying problems like stress on the joints or your dog being overweight. Here are some signs to look out for:
- Limping or Stiffness
- Slow to Get Up or Move Around
- Reluctance to Stand
- Avoid Stairs
- Issues Getting In and Out of a Car
- Loss of Interest in Walks or Exercise
Even if your dog is not suffering from these issues, glucosamine can be used as a preventative measure, too. It can help slow the potential progression of joint issues and help keep your dog healthy before symptoms occur.
Benefits of Glucosamine for Dogs
Relieves Joint Discomfort and Stiffness
- Long-term joint support for aging dogs
- Reduces joint stiffness from daily activities
Supports Strength and Flexibility
- Helps maintain tissue pliability
- Ensures joints stay flexible and lubricated
Enhanced Joint & Bone Health
- Fatty Acids Provide Vital Nutrients for Everyday Health
- Helps reduce inflammation in joints
Promotes A More Active Lifestyle
- Increased Energy and Mobility
- More Playtime
What You Need In The Perfect Glucosamine Supplement
Taking all of the healthful attributes listed above into consideration, we've boiled down a list of four key characteristics you should always look for in quality Glucosamine supplements for dogs. Try to seek out all of these qualities:
Healthy, Safe Ingredients & Dosages
Your dog deserves the best. When it comes to joint support, make sure you’re getting the best, cleanest ingredients possible.
Glucosamine is an amazing substance known to reduce inflammation and increase mobility and joint health. There are some studies that even support the claims that glucosamine supplements potentially slow down the progression of arthritis.[1]
Your dog’s body naturally produces glucosamine (technically known as Glycosaminoglycan), so a proper dosage in a supplement is vital. You need to take into consideration the dog’s weight and the severity of their joint condition. Find a glucosamine supplement that has easy-to-follow serving instructions and that can easily be broken in half to give smaller dogs the perfect amount of Glucosamine.
While Glucosamine is beneficial on its own, combining it with other safe ingredients can be even more beneficial, such as MSM and Chondroitin. This combination can lead to a quicker, better response.[3,4]
Increases Strength
In addition to relieving pain, everything you provide your dog should be beneficial in one way or another. For instance, you give them food that will build their muscle and bone strength and provide much-needed nutrients. You wouldn’t buy a brand that doesn’t have this goal in mind. The same goes for supplements.
When it comes to glucosamine and joint support supplements, make sure it has ingredients that are actively working to build strength in your dog’s muscles, joints, and bones.
Beneficial For Dogs Of All Ages
Although many items throughout your dog’s life are targeted for specific ages, joint support supplements don’t have to operate this way. In fact, we highly recommend choosing a supplement that is good for all ages. Starting these early can be a great form of preventative care as your dog grows, especially for puppies that are predisposed to joint tissue disease.
One of the biggest complaints we hear from dog owners is that their dog has no interest in taking supplements or pills. Dogs, like humans, can be picky. Take into consideration what your dog likes and dislikes. This may be a trial-and-error process, but worth it in the end.
What To Avoid when buying Glucosamine Supplement
Artificial Colors & Dyes
Artificial colors make things look more visually appealing. However, artificial colors have been linked to hyperactivity as well as several biochemical processes within the body. The only reason artificial colors are used in any food is to make the food look better to you. Completely unnecessary for people and pets. And there's no reason to use artificial coloring in food. There are many naturally derived colors available to manufacturers.
Harmful Preservatives
Labels on supplements are sometimes created with the intention of being deceiving or confusing to the consumer. This is due to the fact that many supplements come with fillers, preservatives, potential allergens, and other unnecessary additives like sugars or food coloring. These additives provide no medical benefit and disregarding them may potentially cause your dog to suffer from allergic reactions or sensitivity.
Sodium nitrite is an approved preservative in pet foods and can be toxic in high doses by causing a blood disorder called methemoglobin. Its accumulation over time in the system has also been linked to cancer, especially when combined with added ascorbic acid (Vitamin C) and alpha-tocopherol (Vitamin E), which are common natural vitamin sources.[5]
When it comes to choosing supplements for your dog, be picky. Check the ingredients and don’t settle for less than healthy.
TOP 5 GLUCOSAMINE SUPPLEMENTS FOR DOGS 2025
Based on our own extensive research, the metrics provided by our PupLiving Ranking System, and consideration of thousands of reviews by Shoppers just like you, we've compiled a list of what we've found to be the top five products in this category, on the market today.
1. PupGrade Joint Support
Total Ranking
1012 votes
9.7/10
A+
Overall GradePROS
- Contains Glucosamine
- Natural Ingredients
- Great For Dogs of All Ages
- Appealing Flavor and Scent
- Made in USA
- Excellent US-based customer service
- 30-day, risk-free, money-back, product guarantee
CONS
- Only Available Online
The Bottom Line
PupGrade’s Joint Support offers an incredible value featuring compact packaging, an enticing, dog-friendly flavor, and a long list of natural ingredients, including glucosamine, packed with many healthful benefits. These US-made, easy-to-consume chews allow for consumption regardless of your pup’s age. Watch your dog jump and bounce like a puppy again, while acting as a prevention for younger dogs predisposed to joint issues.
Feed your dog with peace of mind knowing this supplement has been tested rigorously to ensure there are no harmful ingredients.
Their return policy includes a 30-day, risk-free, money-back guarantee, proving the company stands behind its products.
offers an incredible value featuring compact packaging, an enticing, dog-friendly flavor, and a long list of natural ingredients, including glucosamine, packed with many healthful benefits. These US-made, easy-to-consume chews allow for consumption regardless of your pup’s age. Watch your dog jump and bounce like a puppy again, while acting as a prevention for younger dogs predisposed to joint issues.
Feed your dog with peace of mind knowing this supplement has been tested rigorously to ensure there are no harmful ingredients.
Their return policy includes a 30-day, risk-free, money-back guarantee, proving the company stands behind its products.
*Results are based on the PupLiving Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn About Our Top Pick2. YuMOVE Joint Supplement
Total Ranking
742 votes
9.1/10
A-
Overall GradePROS
- Natural Ingredients
- Contains Glucosamine
- Effective Ingredients
- Manufactured in the US
- 60-day money-back guarantee
CONS
- Doesn't Contain Perna Canaliculus
- Expensive
- Different orders for different sized dogs
- Only Available Online
The Bottom Line
The YuMove Natural Joint Health Supplement is one of the higher recommended options on Amazon. Boasting high amounts of glucosamine, green-lipped mussel, and omega-3, this daily chew is designed to provide support and lubrication to aching, stiff joints.
Though this chew has rave reviews, there are a few cons we want to point out. First, this supplement is $15 more expensive than the PupGrade chews, yet they have the same amount of chews in the container. YuMove also sells different jars depending on your dog’s size, so be wary if you own different sized dogs.
*Results are based on the PupLiving Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn More3. Mobility Bites
Total Ranking
644 votes
8.7/10
B+
Overall GradePROS
- Contains Glucosamine
- Multiple Flavors
- 100% Lifetime Satisfaction Guarantee
- Made in the US
CONS
- Doesn't Contain Perna Canaliculus
- Potential Illness
- No live customer service
The Bottom Line
Zesty Paws was started in 2014, promising “premium products and supplements designed to help [pets] feel their best,” according to their About page. This combined with the stunning reviews meant it was a heavy hitter that we needed to check out.
Packed full of healthful ingredients, this supplement chew is a favorite of many pups and owners alike. With multiple flavor options and a reasonable price, this US-made product is a great solution to your pet’s joint pain. Just like PupGrade, Zesty Paws offers an auto-ship option, so your dog will never be without their favorite treat!
As wonderful as this product is, we do want to note that this product may not be for everyone. There have been several customers who noted that their pet became sick after using the Mobility Bites. Monitor your dog and consult your veterinarian before administering.
*Results are based on the PupLiving Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn More4. Glucosamine Soft Chews
Total Ranking
497 votes
8.1/10
B-
Overall GradePROS
- Includes Glucosamine
- Powerful Blend
- For Dogs of All Breeds, Ages, & Sizes
- Cold-Press Extrusion
- Made in the USA
CONS
- Expensive
- Large Breeds Take Many Chews
- Not for Sensitive Guts
The Bottom Line
Doggie Dailies’ Glucosamine Soft Chews are very transparent about how much of each ingredient is present, which is important in terms of giving your pup glucosamine supplements. Their powerful blend not only includes glucosamine, but other powerful ingredients to help with your dog’s joints.
They use a Cold-Press Extrusion to help preserve the ingredients to ensure maximum potency for your dog, regardless of breed, age, or size.
That being said, this product is not cheap if you have a larger dog. Each jar comes with 225 soft chews, but if your dog is 75 pounds or more, they must take a total of six chews to receive the recommended dosage. Additionally, a few dogs have experience bowel issues, so if your dog has a super sensitive gut these may not be for you.
*Results are based on the PupLiving Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn More5. Hip & Joint Supplement
Total Ranking
247 votes
7.9/10
C+
Overall GradePROS
- Contains Glucosamine
- No Fillers
- Great for picky dogs
- For dogs of all sizes and ages
CONS
- Doesn't Contain Perna Canaliculus
- Expensive
- Lower active ingredient amounts
The Bottom Line
From the cute packaging to the adorable name, Rocco & Roxie Hip & Joint Supplement is a favorite consumer product. Boasting high-quality chews that act fast to relieve joint stiffness and pain, Rocco & Roxie’s joint product is full of natural ingredients and free of artificial fillers.
Many users have noted that their liver flavor has enticed even the pickiest of dogs. If your pup will turn their nose up at most treats, this may be a good choice for you. No matter the breed or size of dog, this chew is perfect.
Now, as we’ve stated with some of our other picks, this jar is a little more expensive; almost $15 more than PupGrade to be exact. However, you do get 120 chews versus the normal 60 count. We also wanted to note that the ingredients, which are similar to PupGrade, are in lower quantities. For instance, the glucosamine in one Rocco & Roxie chew is 450 mg versus one PupGrade chew being 500 mg. This may not be a deal-breaker, but is noteworthy.
*Results are based on the PupLiving Ranking System and do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.
Learn MoreFinal Thoughts
The Bottom Line
When it comes to choosing a glucosamine supplement for your pup, it is essential to choose a product that is made with high-quality ingredients, providing natural sources of Glucosamine HCL, MSM & Green Lipped Mussel, that are delivered in potent doses.
After searching the internet to find the best dog glucosamine supplements and evaluating them based on their customer service, ingredients and pricing, we believe PupGrade Joint Support is the best on the market.
PupGrade provides a 100% satisfaction guarantee & 30-day money-back guarantee on all orders!
Take advantage of this Offer while supplies last - Use code below:
Resources:
- Staff, A. K. C. (2022, May 26). Can glucosamine for dogs help treat arthritis and joint pain? American Kennel Club. Retrieved February 20, 2023, from https://www.akc.org/expert-advice/health/glucosamine-dogs-arthritis-joint-pain/
- Hoffman, J. M., Tolbert, M. K., & Promislow, D. E. (2022). Demographic factors associated with joint supplement use in dogs from the Dog Aging Project. Frontiers in Veterinary Science, 9. https://doi.org/10.3389/fvets.2022.906521
- Bhathal, A., Spryszak, M., Louizos, C., & Frankel, G. (2017). Glucosamine and chondroitin use in canines for osteoarthritis: A review. Open veterinary journal, 7(1), 36–49. https://doi.org/10.4314/ovj.v7i1.6
- Butawan, M., Benjamin, R. L., & Bloomer, R. J. (2017). Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement. Nutrients, 9(3), 290. https://doi.org/10.3390/nu9030290
- Worth, A. J., Ainsworth, S. J., Brocklehurst, P. J., & Collett, M. G. (1997). Nitrite poisoning in cats and dogs fed a commercial pet food. New Zealand veterinary journal, 45(5), 193–195. https://doi.org/10.1080/00480169.1997.36025
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